1072895-79-4

Basic information

• Product Name: 1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione
• Synonyms: 1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione
• CAS NO: 1072895-79-4
• Molecular Formula: C7H8N4O2
• Molecular Weight: 180.16402
• Mol File: 1072895-79-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300℃
• Appearance: /
• CAS DataBase Reference: 1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione(1072895-79-4)
• EPA Substance Registry System: 1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione(1072895-79-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1072895-79-4(Hazardous Substances Data)

Usage

General Description

1,3-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-d]-pyrimidine-4,6-dione, also known as febuxostat, is a medication used for the treatment of gout. It works by reducing the production of uric acid in the body, which can help to prevent gout attacks. Febuxostat is a xanthine oxidase inhibitor, meaning it inhibits the enzyme responsible for the conversion of purines to uric acid. By reducing uric acid levels, febuxostat can help to alleviate the symptoms of gout and prevent the formation of urate crystals in the joints. This chemical compound is available in oral tablet form and is typically prescribed for individuals who have not responded well to other gout medications or who have experienced intolerable side effects from other treatments. However, febuxostat may also have potential side effects and interactions with other medications, so it should be used under the supervision of a healthcare professional.

Upstream product

• 3524-32-1 5-Amino-1,3-dimethylpyrazole 
• 1072895-72-7 bis(pentafluorophenyl)imidodicarbonate 
• 101080-17-5 5-amino-1,3-dimethyl-1H-pyrazole-4-carboxamide 
• 57-13-6 urea 

Downstream Products

• 1072895-86-3 4,6-dichloro-1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidine 

Relevant articles and documents

PYRAZOLOPYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. [Fomula I]