1072896-33-3Relevant academic research and scientific papers
The α-Glycosidation of Partially Unprotected N-Acetyl and N-Glycolyl Sialyl Donors in the Absence of a Nitrile Solvent Effect
Aoyagi, Taku,Ohira, Shuichi,Fuse, Shinichiro,Uzawa, Jun,Yamaguchi, Yoshiki,Tanaka, Hiroshi
, p. 6968 - 6973 (2016)
The synthesis of α-sialosides is one of the most difficult reactions in carbohydrate chemistry and is considered to be both a thermodynamically and kinetically disfavored process. The use of acetonitrile as a solvent is an effective solution for the α-sel
Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors
Abdu-Allah, Hajjaj H. M.,Tamanaka, Taichi,Yu, Jie,Zhuoyuan, Lu,Sadagopan, Magesh,Adachi, Takahiro,Tsubata, Takeshi,Kelm, Soerge,Ishida, Hideharu,Kiso, Makoto
experimental part, p. 6665 - 6681 (2009/11/30)
Sialosides incorporating substituted amides or amines at 9-position of sialic acid moiety have been synthesized and evaluated as CD22 inhibitors. Several derivatives exhibited inhibitory potency in sub- to low micromolar range (e. g., 80, 9d, 9g, and 9k s
