107290-27-7

Basic information

• Product Name: Benzenemethanol, 6-bromo-2,3-dimethoxy-
• CAS NO: 107290-27-7
• Molecular Formula: C9H11BrO3
• Molecular Weight: 247.089
• Mol File: 107290-27-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 6-bromo-2,3-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 6-bromo-2,3-dimethoxy-(107290-27-7)
• EPA Substance Registry System: Benzenemethanol, 6-bromo-2,3-dimethoxy-(107290-27-7)

Safety Data

• Hazardous Substances Data: 107290-27-7(Hazardous Substances Data)

Upstream product

• 86-51-1 2,3-dimethyoxybenzaldehyde 
• 5653-67-8 2,3-dimethoxybenzyl alcohol 
• 53811-50-0 6-bromo-2,3-dimethoxybenzaldehyde 

Downstream Products

• 1032644-62-4 C₁₈H₃₁BrO₃Si 
• 175844-54-9 6-bromo-2,3-dimethoxybenzyl bromide 
• 220956-31-0 1-bromo-3,4-dimethoxy-2-((methoxymethoxy)methyl)benzene 
• 53811-50-0 6-bromo-2,3-dimethoxybenzaldehyde 

Relevant articles and documents

DOPAMINE RECEPTOR D1 AGONISTS AND METHODS OF USE

Described herein are small molecule agonists of dopamine receptor D1 that inhibit YAP/TAZ, compositions, and methods of using these compounds and compositions.

An efficient synthesis of 4-isochromanones via Parham-type cyclization with Weinreb amide

The synthesis of 4-isochromanones via Parham-type cyclization with Weinreb amide as the internal electrophilic group, t-BuLi as the lithium reagent was described. The reaction was efficient and could be completed in one minute. The application scope of this new protocol was investigated and the desired products could be obtained in good to excellent yields. Besides, the synthetic potential of this method was further demonstrated by the synthesis of natural product (±)-XJP, which was obtained in six steps with overall yield up to 54%.

Novel hybrids of natural isochroman-4-one bearing N-substituted isopropanolamine as potential antihypertensive candidates

A series of novel hybrids of natural isochroman-4-one bearing isopropanolamine moiety were designed, synthesized and evaluated for their antihypertensive activity. It was found that compound IIId, prepared by hybridizing N-isopropyl substituted isopropanolamine functionality to a phenolic oxygen of isochroman-4-one, exhibited potent β1-adrenoceptor blocking effect comparable to the well-known antihypertensive drug propranolol. Additionally, IIId significantly reduced the systolic and diastolic blood pressure in SHRs by over 40%, which was obviously stronger than the lead compounds 7,8-dihydroxy-3-methyl-isochroman-4-one (XJP) and its analogue XJP-B. Overall, IIId may be a promising antihypertensive candidate for further investigation.