1072930-86-9

Basic information

• Product Name: 1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene
• Synonyms: 1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene;1-(Benzyloxy)-2-(3-methoxystyryl)benzene
• CAS NO: 1072930-86-9
• Molecular Formula: C₂₂H₂₀O₂
• Molecular Weight: 316
• EINECS: 1312995-182-4
• Mol File: 1072930-86-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 471.1±14.0 °C(Predicted)
• Appearance: cream
• Density: 1.124±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene(1072930-86-9)
• EPA Substance Registry System: 1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene(1072930-86-9)

Safety Data

• Hazardous Substances Data: 1072930-86-9(Hazardous Substances Data)

Usage

General Description

1-[2-(3-Methoxyphenyl)ethenyl]-2-(phenylmethoxy)benzene is a synthetic, organic compound, constructed from a significance of complex individual structures such as benzene rings. The former holds an attached substituent comprising of an ethenyl and a methoxyphenyl group, and a later holds an attached substituent that is a phenylmethoxy group. The presence of these components gives this compound aromatic properties, where its behavior is influenced by the interactions of its aromatic rings, as well as its substituted functional groups. As a high purity specialty chemical, it's typically utilized in research and development applications, though clear details about its specific uses are currently limited. It's essential for users to handle this compound with great care, considering the necessary safety precautions due to its chemical properties.

InChI:InChI=1S/C22H20O2/c1-23-21-12-7-10-18(16-21)14-15-20-11-5-6-13-22(20)24-17-19-8-3-2-4-9-19/h2-16H,17H2,1H3/b15-14+

Upstream product

• 60815-18-1 diethyl [(3-methoxyphenyl)methyl]phosphonate 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 
• 824-98-6 m-methoxybenzyl chloride 
• 122-52-1 triethyl phosphite 
• 626-20-0 3-methoxystyrene 
• 31575-75-4 2-bromophenyl benzyl ether 
• 2398-37-0 3-methoxyphenyl bromide 

Downstream Products

• 167145-13-3 2-[2-(3-methoxyphenyl)ethyl]phenol 

Relevant articles and documents

Preparation method of sarpogrelate hydrochloride intermediate

The invention discloses a preparation method of sarpogrelate hydrochloride intermediate (2-hydroxy-3'-methoxy diphenylethane). According to the preparation method, m-bromoanisole, ethane, and o-benzyloxybromobenzene are taken as initial raw materials, an inorganic base is taken as an auxiliary agent, a palladium catalyst is adopted for catalysis, and o-benzoxy-3'-methoxy toluylene is obtained via reaction; o-benzoxy-3'-methoxy toluylene is subjected to hydrogenation debenzylation so as to obtain 2-hydroxy-3'-methoxy diphenylethane. The raw materials are common chemical raw materials, are cheap, and are high in safety; separation of by-products obtained in reaction process is relatively simple; separation is complete; steps are few; on-pot-method is adopted; and product yield is increased.

Synthesis method of 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene

The invention provides a method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene. The method comprises the following steps: making diphenylmethoxyphosphine react with m-methoxybenzyl chloride at 55-60 DEG C to obtain m-methoxybenzyldiphenylphosphine oxide; adding a solvent and a basifier into the m-methoxybenzyldiphenylphosphine oxide; and keeping reactions at room temperature to obtain 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene. The synthesis preparation method is simple, mild in reaction and easy to implement.

New method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene

The invention provides a new method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene. The method comprises the following steps: adding diphenylmethoxyphosphine and m-methoxybenzyl chloride in a molar ratio of 1:(1-1.2) into a reaction device; heating to 55-60 DEG C while stirring, and keeping reactions for 10-12h at the temperature; after the reactions, cooling to room temperature to obtain m-methoxybenzyldiphenylphosphine oxide; adding a solvent and a basifier into the m-methoxybenzyldiphenylphosphine oxide, controlling the temperature at 10-20 DEG C and further dropwise adding the solvent; preserving heat for 5-8h at 10-20 DEG C; performing reduced-pressure recovery of the solvent to dryness, and adding water and stirring and filtering; and washing the material to neutrality and drying at 55-60 DEG C to obtain 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene. The synthesis preparation method is simple, mild in reactionand easy to implement.