107311-58-0Relevant academic research and scientific papers
A model for compounds active against human rhinovirus-14 based on X-ray crystallography data
Diana,Treasurywala,Bailey,Oglesby,Pevear,Dutko
, p. 1306 - 1311 (2007/10/02)
A number of (oxazolinylphenyl)isoxazoles have been synthesized and tested against human rhinovirus-14 (HRV-14). Several of the more active compounds have been examined by X-ray crystallography and their orientation in the compound binding site on the caps
Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents
-
, (2008/06/13)
Compounds of the formula STR1 wherein: Y is an alkylene bridge of 3-9 carbon atoms; Z is N or HC; R is hydrogen or lower-alkyl of 1-5 carbon atoms, with the proviso that when Z is N, R is lower-alkyl; R1 and R2 are hydrogen, halogen, lower-alkyl, lower-alkoxy, nitro, lower-alkoxycarbonyl or trifluoromethyl; and Het is selected from specified heterocyclic groups, are useful and antiviral agents, particularly against picornaviruses, including numerous strains of rhinovirus.
