1073128-07-0Relevant academic research and scientific papers
Et3N-induced demethylation-annulation of 3-alkynyl-4-methoxy-2- pyridones and structurally related compounds in the synthesis of furan-fused heterocycles
Conreaux, David,Belot, Sebastien,Desbordes, Philippe,Monteiro, Nuno,Balme, Genevieve
supporting information; scheme or table, p. 8619 - 8622 (2009/04/11)
(Chemical Equation Presented) Various 3-iodo-4-methoxypyridin-2-ones and related pyrone and coumarin derivatives have been demonstrated as readily available precursors of 2-substituted furan-fused heterocycles by means of in situ sequential Sonogashira-acetylide coupling, dealkylation, and regioselective furan annulation reactions. A Et3N-induced SN2 process has been established that accounts for the dealkylation process.
