1073159-81-5

Upstream product

• 1073159-78-0 N-(2-cyano-3-methyl-phenyl)-N-dimethanesulfonamide 
• 74-88-4 methyl iodide 
• 1184-85-6 N-methylmethane sulphonamide 
• 198633-76-0 2-fluoro-6-methyl-benzonitrile 

Downstream Products

• 1073159-80-4 N-(2-aminomethyl-3-methyl-phenyl)-N-methyl-methanesulfonamide acetate 
• 869371-52-8 N-(2-(aminomethyl)-3-methylphenyl)-N-methylmethanesulfonamide 

Relevant academic research and scientific papers

PYRROLOPYRIMIDINES AS FAK AND ALK INHIBITERS FOR TREATMENT OF CANCERS AND OTHER DISEASES

Disclosed are compounds which inhibit the activity of focal adhesion kinase (FAK) and anaplastic lymphoma kinase (ALK), compositions containing the compounds, and methods of treating diseases during which FAK and ALK are expressed. The diseases are, for example, cancers.

SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH

The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.