1073159-86-0

Upstream product

• 1073159-84-8 N-(2-cyano-5-methyl-phenyl)-N-(methylsulfonyl)methanesulfonamide 
• 74-88-4 methyl iodide 
• 1184-85-6 N-methylmethane sulphonamide 
• 85070-67-3 2-fluoro-4-methylbenzonitrile 

Downstream Products

• 1073159-85-9 N-(2-aminomethyl-5-methyl-phenyl)-N-methyl-methanesulfonamide acetate 
• 1226992-78-4 N-(2-aminomethyl-5-methyl-phenyl)-N-methyl-methane-sufohonamide 

Relevant academic research and scientific papers

2,4-DIAMINOPYRIMIDINE DERIVATES AS PTK2- INHIBITORS FOR THE TREATMENT OF ABNORMAL CELL GROWTH

The present invention encompasses compounds of general formula (1) wherein R1-R3 and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.

SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH

The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.