1073174-91-0Relevant academic research and scientific papers
Anion relay chemistry: Access to the type II ARC reaction manifold through a fundamentally different reaction pathway exploiting 1-oxa-2-silacyclopentanes and related congeners
Smith III, Amos B.,Tong, Rongbiao,Kim, Won-Suk,Maio, William A.
, p. 8904 - 8907 (2011/10/19)
Distinctly different: Two 1-oxa-2-silacyclopentenes and a saturated congener have been synthesized and demonstrated to provide access to type II anion relay chemistry (ARC) through a fundamentally new mechanistic pathway. Similar to previous studies, but contrary to initial hypothesis, Brook rearrangement additives (hexamethylphosphoramide and CuI) are necessary to promote Si migration and anion capture.
Ortho-TMS benzaldehyde: An effective linchpin for type II anion relay chemistry (ARC)
Smith III, Amos B.,Kim, Won-Suk,Wuest, William M.
supporting information; experimental part, p. 7082 - 7086 (2009/04/07)
(Chemical Equation Presented) ARC de triomphe: Ortho-TMS benzaldehyde permits efficient multicomponent union of a variety of nucleophiles and electrophiles, including the first example of a Pd-mediated ARC Type II process. A proof-of-concept synthetic sequence was designed and implemented for construction of a focused library of natural product-like compounds (see scheme). ARC: anion relay chemistry.
