1073190-52-9Relevant academic research and scientific papers
3,6-DISUBSTITUTED XANTHYLIUM SALTS
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Page/Page column 87, (2010/07/02)
This invention pertains generally to processes, uses, methods and materials utilising particular xanthylium compounds, including compounds of formula (I) and (II), as further defined herein. These compounds are useful as drugs, for example, in the treatment of tauopathies, such as Alzheimer's disease.
Synthesis of 5- and 6-carboxy-x-rhodamines
Uddin, Md Jashim,Marnett, Lawrence J.
supporting information; experimental part, p. 4799 - 4801 (2009/05/31)
(Equation Presented) An efficient route is reported to 5- and 6-carboxy-X-rhodamines (compounds 1 and 2) that contain multiple n-propylene or y,y-dimethylpropylene groups bridging terminal nitrogen atoms and the central xanthene core. Gram quantities of these dyes are synthesized from inexpensive starting materials. The isolated products are activated by selective transformation of the carboxylic acid group into N-hydroxysuccinimidyl esters in situ and then conjugated with an amino group of a molecule of interest.
