107323-55-7

Upstream product

• 62938-08-3 3,5-di-tert-butylbenzyl bromide 
• 183289-19-2 C₃₀H₄₄Br₂ 
• 154492-64-5 2-bromo-1-(bromomethyl)-3,5-di-tert-butylbenzene 
• 183289-20-5 C₃₀H₄₄Li₂ 

Downstream Products

• 107323-57-9 1,2-Bis<3,5-di(tert-butyl)phenyl>-1,2-ethandiyl-bisacetat 
• 107323-58-0 1,2-Bis<3,5-di(tert-butyl)phenyl>-1,2-ethandiol 
• 107323-54-6 Bis<3,5-di(tert-butyl)phenyl>acetaldehyd 
• 107323-56-8 1,2-Bis<3,5-di(tert-butyl)phenyl>-1,2-dibromethan 

Relevant academic research and scientific papers

A well-defined low-valent cobalt catalyst Co(PMe3)4 with dimethylzinc: a simple catalytic approach for the reductive dimerization of benzyl halides

Herein, we report the first catalytic version of a cobalt-catalysed reductive homocoupling of benzyl halides which proceeds with low catalyst loadings (0.5 to 5 mol%). By synthetizing each cobalt intermediate we demonstrate that reaction proceeds through two single electron transfers (SET) and that dimethylzinc is only involved in the regeneration of the catalytic species.

Straightforward synthesis of substituted dibenzyl derivatives

The C-C bond formation by homogeneous catalysis is a powerful tool in organic synthesis. The replacement of noble metal by cheaper one for already reported methodologies is of interest for an economical purpose. The attractivity of such replacement is also enhanced if a first raw transition metal is found to be active in several processes. This work demonstrates that a common nickel complex can be used for a two-step cross-coupling procedure, namely a homocoupling reaction of benzyl derivatives and a subsequent Suzuki reaction. These consecutive reactions permit the synthesis of new polyfunctionalized dibenzyl compounds.

Application of 1,2-bis(2-bromo-3,5-di-t-butylphenyl)ethane to preparation of compounds having two diphosphene units

A sterically crowded bromobenzene, 1,2-bis(2-bromo-3,5-di-t-butylphenyl)ethane, was prepared and converted to the corresponding phosphonous dichloride, which reacted with lithium (2,4,6-tri-t-butylphenyl)phosphide to give 1,2-bis[3,5-di-t-butyl-2-{(2,4,6-

The Influence of Steric and Electronic Effects on the Stability of Aldonitrones and on their Conversion into Isoxazolidines

The nitrones 3Aa-Ai were isolated from the reaction of tert-butylhydroxylamine (1A) with aldehydes 2a-i. 1B-D react in an analogous manner. 3Aa-Ac convert slowly into the isoxazolidines 5Aa-Ac, whereas 3Ad-Ai do not.Phenylhydroxylamine (1F) reacts with 2a-d to yield 5Fa-Fd, likewise compounds 5Ea, Ed and the rearranged product 5Ub are formed from 1E.Reaction of 1F and 2f-h, however, yields the nitrones 3Ff-Fh. 3Ff exists in an equilibrium with a dimer of structure 6. - Compounds 5Aa-Ac were found to undergo cycloreversion to give the nitrones 3 in solution, whereas 5Fa-Fd as well as 5Ea, Ub, and Ed did not.There is a steady decrease in the tendency for cycloreversion in the order 5Ab > 5Bb > 5Cb, however, the degree of cycloreversion is also solvent-dependent.Acyclic compounds 7 were found to be intermediates in the conversion of 5Aa and Bb into the corresponding nitrones.Compound 9, formed from 1A and acrolein (8), does not decompose to yield its components 3Aa and 11.The influence of electronic and steric effects on the relative stability of the nitrones 3 and isoxazolidines 5 is discussed.