1073239-46-9

Upstream product

• 53681-47-3 6-amino-1-propyl-1H-pyrimidine-2,4-dione 
• 622-95-7 4-chlorobenzyl bromide 

Downstream Products

• 1073239-45-8 6-amino-3-(4-chlorobenzyl)-5-nitroso-1-propylpyrimidine-2,4(1H,3H)-dione 
• 1073238-78-4 8-azetidin-1-yl-1-(4-chlorobenzyl)-7-methyl-3-propyl-3,7-dihydro-1H-purine-2,6-dione 
• 1073238-92-2 1-(4-chlorobenzyl)-8-(1-hydroxyethyl)-7-methyl-3-propyl-3,7-dihydro-1H-purine-2,6-dione 
• 1073239-43-6 1-(4-chlorobenzyl)-8-(1-hydroxyethyl)-3-propyl-3,7-dihydro-1H-purine-2,6-dione 
• 1073238-77-3 1-(4-chlorobenzyl)-8-(dimethylamino)-7-methyl-3-propyl-3,7-dihydro-1H-purine-2,6-dione 
• 1073238-90-0 8-bromo-1-(4-chlorobenzyl)-7-methyl-3-propyl-3,7-dihydro-1H-purine-2,6-dione 
• 1073239-50-5 C₁₅H₁₄BrClN₄O₂ 
• 896420-11-4 1-(4-chlorobenzyl)-3-propyl-3,7-dihydro-1H-purine-2,6-dione 

Relevant academic research and scientific papers

Diazinane Compounds

The present invention relates to novel compounds of the general formula (I) wherein R1, R2, R3 and R4 are as defined, having a positive allosteric GABAB receptor (GBR) modulator effect, methods for the preparation of said compounds and to their use, optionally in combination with a GABAB agonist, for the inhibition of transient lower esophageal sphincter relaxations, for the treatment of gastroesophageal reflux disease, as well as for the treatment of functional gastrointestinal disorders and irritable bowel syndrome (IBS).

XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT

The present invention relates to novel xanthine compounds of the general formula (I) wherein R1, R2, R3 and R4 are as defined, having a positive allosteric GABA Breceptor (GBR) modulator effect, methods for the preparation of said compounds and to their use, optionally in combination with a GABA Bagonist, for the inhibition of transient lower esophageal sphincter relaxations, for the treatment of gastroesophageal reflux disease, as well as for the treatment of functional gastrointestinal disorders and irritable bowel syndrome (IBS).