1073277-32-3Relevant academic research and scientific papers
Synthesis of enantiopure 1-arylprop-2-en-1-ols and their tert-butyl carbonates
Stambasky, Jan,Malkov, Andrei V.,Kocovsky, Pavel
, p. 9148 - 9150 (2008)
(Chemical Equation Presented) Enantiomerically pure 1-arylpropenols 8 have been prepared by resolution of the corresponding racemates, using the lipase formulation Novozyme 435. Deprotonation of the latter alcohols with n-BuLi, followed by derivatization with (t- BuO)2CO, afforded the corresponding carbonates 5. Optimization of the process is presented.
