1073339-07-7 Usage
Description
2-(2,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a boron-containing chemical compound utilized in organic synthesis as a boronic ester. Characterized by a boron atom bonded to two oxygen atoms and a phenyl group, this compound features tetramethyl substitution on the boron atom, which imparts significant steric hindrance. This structural attribute renders it a highly valuable reagent in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. Furthermore, its potential extends to various applications, such as serving as a building block in drug discovery and material science, underscoring its versatility and importance in the realm of chemical research and development.
Uses
Used in Organic Synthesis:
2-(2,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a boronic ester in organic synthesis for its steric hindrance and reactivity in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of carbon-carbon bonds.
Used in Drug Discovery:
In the pharmaceutical industry, 2-(2,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is used as a building block for the development of new drugs, leveraging its unique structural properties to create novel molecular entities with potential therapeutic applications.
Used in Material Science:
2-(2,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is also utilized as a component in material science, where its incorporation into new materials can lead to advancements in material properties and functionalities.
Check Digit Verification of cas no
The CAS Registry Mumber 1073339-07-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,3,3,3 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1073339-07:
(9*1)+(8*0)+(7*7)+(6*3)+(5*3)+(4*3)+(3*9)+(2*0)+(1*7)=137
137 % 10 = 7
So 1073339-07-7 is a valid CAS Registry Number.
1073339-07-7Relevant articles and documents
Ortho-Selective C-H Borylation of Aromatic Ethers with Pinacol-borane by Organo Rare-Earth Catalysts
Xue, Can,Luo, Yong,Teng, Huailong,Ma, Yuanhong,Nishiura, Masayoshi,Hou, Zhaomin
, p. 5017 - 5022 (2018/05/14)
The regioselective C-H borylation of aromatic ethers such as anisoles is of much interest and importance, but has remained a challenge to date. We report herein the catalytic ortho-selective C-H borylation of a wide range of aromatic ethers with pinacolborane (HBpin) by rare-earth metallocene complexes. This protocol offers an efficient and straightforward route for the synthesis of a variety of borylated aromatic ether derivatives. A proper metal/ligand combination for the rare-earth metal catalysts was found to be critically important to promote this transformation.
METHOD FOR PREPARING AMINOARYLBORANE COMPOUNDS OR DERIVATIVES THEREOF
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Page/Page column 92; 93, (2015/06/18)
The present invention provides a process for the preparation of aminoarylborane compounds and derivatives thereof comprising a step of arylation by reacting an aryl chloride with an aminoborane compound in the presence of a catalytic system.
Nano-Fe2O3-catalyzed direct borylation of arenes
Yan, Guobing,Jiang, Yubo,Kuang, Chunxiang,Wang, Shuai,Liu, Haichao,Zhang, Yan,Wang, Jianbo
, p. 3170 - 3172 (2010/08/06)
Nano-Fe2O3-catalyzed borylation of arenes with diboron pinacol ester B2pin2 has been found to give borylation products with selectivity controlled by electronic effects of substituents. The Royal Society of Chem
