1073339-21-5

Basic information

• Product Name: 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
• Synonyms: 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(trifluoromethyl)benzene
• CAS NO: 1073339-21-5
• Molecular Formula: C₁₃H₁₆BF₃O₂
• Molecular Weight: 272.0711496
• EINECS: 932-590-9
• Product Categories: B (Classes of Boron Compounds);Boronic Acids Esters
• Mol File: 1073339-21-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 73 °C / 2mmHg
• Appearance: /
• Density: 1.15
• CAS DataBase Reference: 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE(1073339-21-5)
• EPA Substance Registry System: 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE(1073339-21-5)

Safety Data

• Hazardous Substances Data: 1073339-21-5(Hazardous Substances Data)

Usage

General Description

2-[2-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a chemical compound with the molecular formula C14H19BF3O2. It is a boron-containing compound with a dioxaborolane structure and a trifluoromethylphenyl group attached to the boron atom. 2-[2-(TRIFLUOROMETHYL)PHENYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE has potential applications in organic synthesis, such as in the formation of carbon-carbon and carbon-heteroatom bonds. It can also be used as a reagent in catalytic reactions and in the preparation of boron-containing pharmaceuticals and agrochemicals due to its unique chemical properties. Additionally, it has the potential for use as a building block in the production of advanced materials and functional organic molecules.

Upstream product

• 98-08-8 α,α,α-trifluorotoluene 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 1423-27-4 2-(trifluoromethyl)phenylboronic acid 
• 312-96-9 2-(trifluoromethyl)benzoyl fluoride 
• 73183-34-3 bis(pinacol)diborane 
• 444-29-1 2-iodo(trifluoromethyl)benzene 
• 312-94-7 2-trifluoromethylbenzoyl chloride 
• 433-97-6 2-trifluoromethylbenzoic acid 
• 392-83-6 o-trifluoromethylphenyl bromide 
• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Downstream Products

• 189065-49-4 4-(3-(trifluoromethyl)phenyl)morpholine 
• 433-95-4 1,2-bis(trifluoromethyl)benzene 
• 441072-21-5 2-(2-(trifluoromethyl)phenyl)pyridine 
• 1158649-32-1 methyl (E)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-(2-(trifluoromethyl)phenyl)acetate 

Relevant articles and documents

Nickel-catalysed decarbonylative borylation of aroyl fluorides

The first Ni(cod)2/PPh3 catalyst system has been established for decarbonylative borylation of aroyl fluorides with bis(pinacolato)diboron. A wide range of functional groups in the substrates were well tolerated. The ease of access of the starting aroyl fluorides indicates that these results might become an alternative to the existing decarbonylation events.

Radical Metal-Free Borylation of Aryl Iodides

A simple metal-free borylation of aryl iodides mediated by a fluoride sp 2 -sp 3 diboron adduct is described. The reaction conditions are compatible with various functional groups. Electronic effects of substituents do not affect the borylation while steric hindrance does. The reaction proceeds via a radical mechanism in which pyridine serves to stabilize the boryl radicals, generated in situ.

The method for producing the phenyl boronic acid ester

PROBLEM TO BE SOLVED: To provide a method for producing phenylboronic acid esters in good yield from diborons and aryl halides by using a nickel catalyst and a base. SOLUTION: In the method for producing phenylboronic acid esters represented by general formula (3), wherein A is an ethylene group or the like which may be substituted by a methyl group, R1is a fluorine atom or the like, and m is an integer of 0-5; diborons and a chlorobenzene derivative are reacted with each other by using a trimethylphosphine coordinated nickel catalyst and alkoxides. COPYRIGHT: (C)2013,JPOandINPIT