1073354-91-2

Basic information

• Product Name: 5-Benzothiazole boronic acid pinacol ester
• CAS NO: 1073354-91-2
• Molecular Formula: C₁₃H₁₆BNO₂S
• Molecular Weight: 279
• Mol File: 1073354-91-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Benzothiazole boronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzothiazole boronic acid pinacol ester(1073354-91-2)
• EPA Substance Registry System: 5-Benzothiazole boronic acid pinacol ester(1073354-91-2)

Safety Data

• Hazardous Substances Data: 1073354-91-2(Hazardous Substances Data)

Usage

General Description

5-Benzothiazole boronic acid pinacol ester is a chemical compound often used in organic synthesis. It belongs to the categories of boronic acid, pinacol esters, and heterocyclic compounds. This chemical is white to off-white in color and appears as a crystalline powder. It is commonly utilized in broad applications, particularly in the fields of pharmaceuticals and material science, and can often be found used as a catalyst or reagent. It's notable for its ability to easily form stable boronic acids, which are crucial in the Suzuki reaction, a popular method of creating carbon-carbon bonds. Handling should be performed with appropriate safety measures due to its irritant properties.

Upstream product

• 768-11-6 5-bromo-benzthiazole 
• 73183-34-3 bis(pinacol)diborane 
• 2786-51-8 5-chlorobenzo[d]thiazole 

Downstream Products

• 1246206-55-2 4-[3-{6-(3-benzothiazol-5-yl-5-ethoxy-phenoxy)-hexyl}-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester 
• 1229205-59-7 6-(benzo[d]thiazol-5-yl)-N-(3,4-dimethoxyphenyl)imidazo[1,2-a]pyrazin-8-amine 
• 1210047-48-5 methyl 2-((4-(1,3-benzothiazol-5-yl)-3-methyl-1-(2-methylphenyl)-1H-pyrazol-5-yl)amino)-5-methoxybenzoate 
• 1186605-08-2 4-[3-[6-(3-benzothiazol-5-yl-5-methanesulfonyl-phenoxy)-hexyl]-2-(2-ethoxycarbonyl-ethyl)-phenoxy]-butyric acid ethyl ester 

Relevant articles and documents

Photocatalytic Cross-Couplings of Aryl Halides Enabled by o-Phosphinophenolate and o-Phosphinothiophenolate

o-Phosphinophenolate and o-phosphinothiophenolate are potent photocatalysts with strong reducing ability to activate aryl chlorides and bromides under visible light for borylation, arylation, and phosphorylation. Experimental and theoretical studies revealed that the o-diphenylphosphino substituent results in a narrow optical gap and facilitates intersystem crossing to access triplet states, which promote phenolate and thiophenolate to function as effective visible-light-photoredox catalysts. The results presented herein suggest promising utility of synthetically modified phenolates and thiophenolates as photoredox catalysts.

PYRIMIDINE SULFAMIDE DERIVATIVE AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF

Disclosed are a series of pyrimidine sulfamide compounds and applications thereof in preparing a drug for a disease related to an ETA receptor antagonist. In particular, disclosed is a derived compound represented by formula (I) or a tautomer or pharmaceutically acceptable composition thereof.

AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS

This invention relates to the use of azabenzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of azabenzimidazoles in the treatment of cancer.