1073355-22-2

Basic information

• Product Name: 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester
• Synonyms: 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester;2-[2-(4-TERT-BUTYLPHENYL)ETHYL]-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE;2-(4-(tert-Butyl)phenethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS NO: 1073355-22-2
• Molecular Formula: C₁₈H₂₉BO₂
• Molecular Weight: 288.23
• Mol File: 1073355-22-2.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester(1073355-22-2)
• EPA Substance Registry System: 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester(1073355-22-2)

Safety Data

• Hazardous Substances Data: 1073355-22-2(Hazardous Substances Data)

Usage

General Description

2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester is a boronic acid derivative that is commonly used in organic synthesis. It is a pinacol ester of the boronic acid derivative, and it is a valuable reagent in Suzuki-Miyaura coupling reactions, which are widely used in the synthesis of biaryl compounds. 2-(4-tert-Butylphenyl)ethylboronic acid pinacol ester is often utilized as a building block in the preparation of pharmaceuticals, agrochemicals, and materials science. It is a highly versatile and important chemical in organic chemistry with various applications in the field of drug discovery and development.

Upstream product

• 7647-01-0 hydrogenchloride 
• 124-38-9 carbon dioxide 
• 1746-23-2 4-tert-Butylstyrene 
• 73183-34-3 bis(pinacol)diborane 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 274-07-7 benzo[1,3,2]dioxaborole 
• 772-38-3 4-tert-Butylphenylacetylene 
• 18880-00-7 1-(bromomethyl)-4-(1,1-dimethylethyl)benzene 
• 78782-17-9 4,4,5,5-tetramethyl-2-[(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl]-1,3,2-dioxaborolane 

Relevant articles and documents

Hidden Boron Catalysis: Nucleophile-Promoted Decomposition of HBpin

Simple nucleophiles with structural similarities to known hydroboration catalysts can readily mediate the formation of BH3 and borohydride species from pinacolborane (HBpin). Alkyne and alkene hydroboration reactions were successfully mediated by nucleophiles through BH3 generation, with BH3-catalyzed hydroboration found to dominate catalysis. NMR spectroscopy and kinetic analyses showed that the nucleophiles NaOtBu, Na[N(SiMe3)2], nBu2Mg, and nBuLi only promoted the formation of BH3 and were not "true" hydroboration catalysts.

Beneficial Effect of a Secondary Ligand on the Catalytic Difunctionalization of Vinyl Arenes with Boron and CO2

The boracarboxylation of vinyl arenes catalyzed by copper(I) is an alkene difunctionalization reaction that provides synthetically useful β-boryl-α-aryl propanoic acid derivatives. Drawbacks of the original reaction methodology are high catalyst loading a

Borohydrogenation reaction method of halide calcium catalyzed olefins

The present invention discloses a method of borohydrogenation of olefins catalyzed by calcium halide, comprising, under anhydrous and anaerobic conditions, calcium halide added to the mixture of olefins and pinacol borane, stirred at 90 to 110 ° C for 6 t

Selective electrocatalytic hydroboration of aryl alkenes

Organoboron compounds are powerful precursors of value-added organic compounds in synthetic chemistry, and transition metal-catalysed borylation has always been dominant. To avoid toxic reagents and costs associated with metal catalysts, simpler, more eco

Site-Fixed Hydroboration of Terminal and Internal Alkenes using BX3/iPr2NEt**

An unprecedented and general hydroboration of alkenes with BX3 (X=Br, Cl) as the boration reagent in the presence of iPr2NEt is reported. The addition of iPr2NEt not only suppresses alkene polymerizat