1073371-77-3

Basic information

• Product Name: 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER;4-Chloro-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline;4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine
• CAS NO: 1073371-77-3
• Molecular Formula: C₁₂H₁₇BClNO₂
• Molecular Weight: 253.53
• Mol File: 1073371-77-3.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 371.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.26±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER(1073371-77-3)
• EPA Substance Registry System: 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER(1073371-77-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 1073371-77-3(Hazardous Substances Data)

Usage

Uses

2-Amino-5-chlorophenylboronic acid, pinacol ester

Upstream product

• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 873-38-1 4-chloro-2-bromoaniline 
• 73183-34-3 bis(pinacol)diborane 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 870556-04-0 4-chloro-2-pyridin-2-yl-phenylamine 
• 1802434-18-9 4-chloro-2-(6-methoxypyrimidin-4-yl)aniline 

Relevant articles and documents

CRYSTALLINE FORMS OF (9R, 135S)-13- {4-[5-CHLORO-2-(4-CHLORO-1H,2,3- TRIAZOL- 1 -YL)PHENYL] -6-OXO- 1,6-DIHYDROPYRIMIDIN- 1-YL}-3-(DIFLUOROMETHYL)-9-METHYL-3,4,7,15- TETRAAZATRICYCLO [ 12.3.1.02·6] OCTADECA- 1(18), 2(6), 4, 14, 16-PENTAEN-8-ONE

Disclosed are crystalline forms of Compound (I). Compound (I) is useful as an anti-thromboembolic agent in the treatment of cardiovascular diseases.

Heterocyclic compound and application thereof

The invention discloses a heterocyclic compound and application thereof. The invention provides a heterocyclic compound shown as a formula I, a stereoisomer thereof or a pharmaceutically acceptable salt thereof. The compound can be used as an FXIa inhibit

Alkoxy pyridone compound as well as preparation method and application thereof

The invention belongs to the field of medicinal chemistry, specifically, the invention relates to a series of inhibitors of factor XIa (FXIa for short) with a novel structure as well as a preparationmethod and an application thereof. The structure is shown as the following general formula (I). These compounds or stereoisomers, racemates, geometric isomers, tautomers, prodrugs, hydrates, solvatesor pharmaceutically acceptable salts and pharmaceutical compositions thereof can be used to treat or/and prevent related diseases mediated by factor XIa (FXIa for short).