1073528-75-2Relevant academic research and scientific papers
Concise enantioselective total synthesis of neopeltolide macrolactone highlighted by ether transfer
Kartika, Rendy,Gruffi, Thomas R.,Taylor, Richard E.
supporting information; experimental part, p. 5047 - 5050 (2009/05/31)
(Chemical Equation Presented) A concise total synthesis of neopeltolide macrolactone has been accomplished in 14 steps in the longest linear sequence, 15 steps overall from commercially available materials. The present synthesis was highlighted by successful exploitation of ether transfer methodology and a radical cyclization reaction to directly establish the requisite stereochemistry of the tetrahydropyran core.
