107356-12-7

Basic information

• Product Name: 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide
• Synonyms: 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide
• CAS NO: 107356-12-7
• Molecular Weight: 399.317
• Mol File: 107356-12-7.mol

Chemical Properties

• CAS DataBase Reference: 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide(107356-12-7)
• EPA Substance Registry System: 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide(107356-12-7)

Safety Data

• Hazardous Substances Data: 107356-12-7(Hazardous Substances Data)

Upstream product

• 87-64-9 2-chloro-6-methylphenol 
• 107356-09-2 3-Chloro-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzoic acid 
• 107356-11-6 3-Chloro-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzaldehyde 
• 98033-85-3 5-(5-bromopentyl)-3-methylisoxazole 
• 107356-10-5 3-Chloro-4-hydroxy-5-methylbenzaldehyde 
• 870-24-6 2-chloroethanamine hydrochloride 
• 118276-20-3 3-Chloro-5-methyl-4-[5-(3-methyl-isoxazol-5-yl)-pentyloxy]-benzoyl chloride 

Relevant articles and documents

Synthesis and Structure-Activity Studies of Some Disubstituted Phenylisoxazoles against Human Picornavirus

A number 2,6-disubstituted analogues of disoxaril, a broad spectrum antipicornavirus agent, have been prepared and evaluated against several rhinovirus serotypes.A QSAR study revealed that the mean MIC () against five rhinovirus serotypes correlated well with log P.The 2,6-dichloro analogue, 15, was highly effective in vitro against rhinoviruses with an MIC80 of 0.3 μM, as well as against several enteroviruses, and was also effective in preventing paralysis in mice infected with coxsackievirus A-9.

Di-heterocyclic compounds and their use as antiviral agents

Compounds of the formulas: STR1 wherein Het is an oxazole or oxazine moiety; X is O, S or SO, n is an integer from 3 to 9, Y is an aliphatic bridge; and the various R groups represent hydrogen or various substituents as described herein, are useful as antiviral agents, especially against picornaviruses. N-(Chloroalkyl)amide intermediates for the compounds of Formula I are also active as antiviral agents. Related compounds outside the scope of the above formulas are also disclosed.