1073608-02-2 Usage
Uses
Used in Pharmaceutical Research:
Cilostazol-d11 is used as a potent phosphodiesterase III A (PDE3A) inhibitor with an IC50 of 0.2 μM. It is employed in the development and study of drugs targeting PDE3A for the treatment of various conditions.
Used in Cardiovascular Research:
Cilostazol-d11 is used as an antithrombotic, vasodilatory, and cardiotonic agent in vivo. It helps researchers understand the mechanisms of action and potential therapeutic applications in cardiovascular diseases.
Used in Lipid Metabolism Studies:
Cilostazol-d11 is used to study its effects on lipid levels in vivo. This helps researchers investigate its potential role in the management of dyslipidemia and related conditions.
Used in Drug Metabolism and Pharmacokinetics Research:
As a deuterated analog, Cilostazol-d11 is used to study the metabolism and pharmacokinetics of the parent compound, Cilostazol. This aids in understanding the drug's absorption, distribution, metabolism, and excretion (ADME) properties, which are crucial for drug development and optimization.
Used in Drug Interaction Studies:
Cilostazol-d11 can be used to investigate potential drug-drug interactions involving PDE3A inhibition, providing valuable insights for the safe and effective use of Cilostazol in combination with other medications.
Check Digit Verification of cas no
The CAS Registry Mumber 1073608-02-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,3,6,0 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1073608-02:
(9*1)+(8*0)+(7*7)+(6*3)+(5*6)+(4*0)+(3*8)+(2*0)+(1*2)=132
132 % 10 = 2
So 1073608-02-2 is a valid CAS Registry Number.
1073608-02-2Relevant academic research and scientific papers
ANALOGUES OF CILOSTAZOL
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Page/Page column 28-29, (2008/12/08)
This invention relates to novel compounds which are derivatives of the phosphodiesterase inhibitor, cilostazol and pharmaceutically acceptable salts thereof. This invention also provides pyrogen- free compositions comprising one or more compounds of the i
