107378-02-9Relevant academic research and scientific papers
Facile Synthesis of Fluorine-containig methanone, 2-Amino-4-aryl-5-arylazothiazoles and 3-Aroyl-4-acetyl/benzoyl-5-methyl-1-phenylpyrazoles through N-Aryl-α-oxo-α-arylethanehydrazonoyl Bromide
Joshi, Krishna C.,Pathak, Vijai N.,Sharma, Sharda
, p. 775 - 779 (2007/10/02)
N-Aryl-α-oxo-α-arylethanehydrazonoyl bromides 2 react with potassium thiocyanate in ethanol leading to the formation of methanone 5 in quantitative yield.Treatment of 2 with thiourea and β-diketones affords 2-amino-4-aryl-5-arylazothiazoles 4 and 3-aroyl-4-acetyl/benzoyl-5-methyl-1-phenylpyrazoles 6 in 65-70 and 60-70percent yields respectively.Compound 5 has also been subjected to acylation and chloroacetylation.All the compounds are characterized by their analytical and spectral (ir, 1H-nmr and ms) data.Mass fragmentation patterns of these compounds are discussed.
