107427-71-4Relevant academic research and scientific papers
Transition-metal-free synthesis of primary to tertiary carboxamides: A quick access to prodrug-pyrazinecarboxamide
Mete, Trimbak B.,Singh, Ankit,Bhat, Ramakrishna G.
, p. 4709 - 4712 (2017)
One-pot expedient and direct carbamoylation of heterocyclics is described. The transformation is realized via direct dehydrogenative aminocarbonylation of heterocyclic compounds under transition-metal-free conditions. This method is regioselective and the protocol is proved to be scalable on a gram scale. Further, the therapeutically useful antitubercular agent pyrazinecarboxamide is successfully synthesized by employing this protocol.
Polycyclic N-Hetero Compounds. XXIV. Reaction of Pyridine and Quinoline N-Oxides with N-Methylformamide
Hirota, Takashi,Namba, Tetsuto,Sasaki, Kenji
, p. 3431 - 3434 (2007/10/02)
Reactions of pyridine and quinoline N-oxides with N-methylformamide are described.N-Methylcarbamoylation occured at the C-2 or C-4 position of pyridine and quinoline derivatives.Keywords - pyridine N-oxide; quinoline N-oxide; N-methylformamide; N-methylcarbamoylation; N-oxide; formamide; carbamoylation
