107462-44-2

Upstream product

• 61350-60-5 Z-L-prolyl chloride 
• 107494-25-7 (1R,3R)-1-Isobutyl-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid methyl ester 
• 107494-24-6 (1R,3S)-methyl 1-isobutyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 
• 61350-60-5 Z-D-prolyl chloride 
• 19746-29-3 (R)-3-(1H-Indol-3-yl)-2-[2-methyl-prop-(E)-ylideneamino]-propionic acid methyl ester 
• 107494-23-5 methyl (1S,3S)-1-isobutyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 
• 590-86-3 isovaleraldehyde 
• 4299-70-1 D-Tryptophan methyl ester 
• 4299-70-1 L-tryptophan methyl ester 
• 19746-29-3 (S)-3-(1H-Indol-3-yl)-2-[2-methyl-prop-(E)-ylideneamino]-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthetic Approaches to Fumitremorgins. III. Synthesis of Optically Active Pentacyclic Ring Systems, and Their Oxidation at Ring C

Pictet-Spengler reaction of L-tryptophan methyl ester (9) and 6-methoxy-L-tryptophan methyl ester (40) with isovaleraldehyde (10) in methylene chloride in the presence of trifluoroacetic acid gave the cis-tetrahydro-β-carboline (11, 41) as the major isome

SYNTHETIC APPROACH TO THE TOTAL SYNTHESIS OF FUMITREMORGINS II SYNTHESIS OF OPTICALLY ACTIVE PENTACYCLIC INTERMEDIATES AND THEIR DEHYDROGENATION

Optically active pentacycles ( l3-18 ) were synthesized from L- and D-tryptophans, two of which ( l3 and 15 ) were alkylated and dehydrogenated to 21 and 22, respectively.