107465-19-0Relevant academic research and scientific papers
DIASTEREOSELECTIVE SYNTHESIS OF 2,3,4-TRISUBSTITUTED γ-LACTOLS AND γ-LACTONES VIA REGIO- AND STEREOCONTROLLED OPENING OF A 1,2-EPOXY-4-HYDROXYALKYL CARBAMATE WITH HETERO-NUCLEOPHILES
Luessmann, Joerg,Hoppe, Dieter,Jones, Peter G.,Fittschen, Christa,Sheldrick, George M.
, p. 3595 - 3598 (2007/10/02)
The acid-catalyzed ring opening of the title epoxide 1 takes place at the C-1 atom with retention of configuration at C-2 to form 2,3-cis-2-hydroxy-substituted γ-lactol derivatives 3.In basic media, nucleophiles attack the C-2 atom with inversion of confi
