107469-26-1

Basic information

• Product Name: 3-nitro-2-[2-(trimethylsilyl)ethynyl]pyridine
• Synonyms: 3-nitro-2-[2-(trimethylsilyl)ethynyl]pyridine
• CAS NO: 107469-26-1
• Molecular Weight: 220.303
• Mol File: 107469-26-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-nitro-2-[2-(trimethylsilyl)ethynyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-2-[2-(trimethylsilyl)ethynyl]pyridine(107469-26-1)
• EPA Substance Registry System: 3-nitro-2-[2-(trimethylsilyl)ethynyl]pyridine(107469-26-1)

Safety Data

• Hazardous Substances Data: 107469-26-1(Hazardous Substances Data)

Upstream product

• 19755-53-4 2-bromo-3-nitropyridine 
• 1066-54-2 trimethylsilylacetylene 
• 5470-18-8 2-Chloro-3-nitropyridine 

Downstream Products

• 947330-64-5 2-((trimethylsilyl)ethynyl)pyridin-3-amine 
• 272-49-1 1H-pyrrolo[3,2-b]pyridine 

Relevant articles and documents

Facile synthesis of 2-substituted 4-azaindoles

A novel and efficient strategy for the synthesis of 2-substituted 4-azaindoles from 2-chloro-3-nitropyridine through Pd-catalyzed Sonogashira cross-coupling, followed by reduction and heteroannulation on t-BuOK, is reported. Copyright Taylor & Francis Group, LLC.

Condensed Heteroaromatic Ring Systems. XII. Synthesis of Indole Derivatives from Ethyl 2-Bromocarbanilates

The palladium-catalyzed reaction of ethyl 2-bromocarbanilate with trimethylsilylacetylene yielded ethyl 2-(trimethylsilylethynyl)carbanilate, which was treated with sodium ethoxide to give indole.The carbanilates having a methyl or a bromo substituent were similarly transformed to corresponding indole derivatives.Furthermore, pyrrolo- and Pyrrolopyridines were synthesized by this method.Keywords---palladium-catalyzed reaction; trimethylsilylacetylene; ethyl 2-halocarbanilate; ethyl 2-halopyridinecarbamate; ethyl 2-(trimethylsilylethynyl)carbanylate; ethyl o-(trimethylsilylethynyl)pyridinecarbamate;indole;pyrrolopyridine