1074762-34-7

Basic information

• Product Name: C₂₅H₂₈F₄N₄O
• CAS NO: 1074762-34-7
• Molecular Weight: 476.517
• Mol File: 1074762-34-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₈F₄N₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₈F₄N₄O(1074762-34-7)
• EPA Substance Registry System: C₂₅H₂₈F₄N₄O(1074762-34-7)

Safety Data

• Hazardous Substances Data: 1074762-34-7(Hazardous Substances Data)

Upstream product

• 905986-91-6 2-trifluoromethyl-benzyl-piperidone 
• 58859-77-1 5-fluoro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one 

Relevant articles and documents

Synthesis and SAR of analogues of the M1 allosteric agonist TBPB. Part I: Exploration of alternative benzyl and privileged structure moieties

This Letter describes the first account of the synthesis and SAR, developed through an iterative analogue library approach, of analogues of the highly selective M1 allosteric agonist TBPB. With slight structural changes, mAChR selectivity was maintained, but the degree of partial M1 agonism varied considerably.