107485-63-2 Usage
Uses
Used in Pharmaceutical Industry:
2-BROMO-6-FLUOROBENZAMIDE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-BROMO-6-FLUOROBENZAMIDE is utilized as a building block in the creation of agrochemicals, such as pesticides and herbicides, to enhance crop protection and yield.
Used in Dye Production:
2-BROMO-6-FLUOROBENZAMIDE is employed as a precursor in the production of dyes, contributing to the development of new colorants for various applications, including textiles, plastics, and printing inks.
Used in Organic Compounds Synthesis:
As a versatile building block, 2-BROMO-6-FLUOROBENZAMIDE is used in the synthesis of other organic compounds, expanding its utility in the chemical industry for the creation of specialty chemicals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 107485-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,4,8 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 107485-63:
(8*1)+(7*0)+(6*7)+(5*4)+(4*8)+(3*5)+(2*6)+(1*3)=132
132 % 10 = 2
So 107485-63-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrFNO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)
107485-63-2Relevant academic research and scientific papers
Discovery of highly potent SARS-CoV-2 Mpro inhibitors based on benzoisothiazolone scaffold
Chen, Weixiong,Chen, Wuhong,Feng, Bo,Han, Sheng,Hu, Youhong,Li, Jia,Wang, Peipei,Zang, Yi
supporting information, (2022/01/14)
The COVID-19 pandemic has drastically impacted global economies and public health. Although vaccine development has been successful, it was not sufficient against more infectious mutant strains including the Delta variant indicating a need for alternative treatment strategies such as small molecular compound development. In this work, a series of SARS-CoV-2 main protease (Mpro) inhibitors were designed and tested based on the active compound from high-throughput diverse compound library screens. The most efficacious compound (16b-3) displayed potent SARS-CoV-2 Mpro inhibition with an IC50 value of 116 nM and selectivity against SARS-CoV-2 Mpro when compared to PLpro and RdRp. This new class of compounds could be used as potential leads for further optimization in anti COVID-19 drug discovery.
