107487-86-5

Upstream product

• 106793-09-3 6-(4-Butyl-phenyl)-2-chloro-nicotinonitrile 
• 1033595-33-3 C₂₃H₂₂N₂O₂ 
• 107487-95-6 6-(4-Butyl-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 37920-25-5 1-(4-butylphenyl)ethanone 

Relevant academic research and scientific papers

Facile synthesis of a series of liquid crystalline 2-(4'-alkylphenyl)-5-cyanopyridines

The invention relates to a facile synthesis of a series of 2-(4′-alkylphenyl)-5-cyanopyridine liquid crystal compounds which are represented by the following formula (I): wherein Cn is a linear alkyl having 1-12 carbon atoms. The synthesis of the liquid crystalline 2-(4′-alkylphenyl)-5-cyanopyridine is completed in a two-step reaction. First, a Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine. Then the 1,2-dihydropyridine is oxidized with o-chloronil to obtain the 2-(4′-alkylphenyl)-5-cyanopyridine.

SYNTHESIS OF 2-(4-ALKYLPHENYL)- AND 2-(4-ALKOXYPHENYL)-5-CYANOPYRIDINES AND THEIR LIQUID-CRYSTAL CHARACTERISTICS

6-(4-Alkylphenyl)- and 6-(4-alkoxyphenyl)-3-cyano-2-pyridones were obtained by the cyclization of 4-(4-alkylphenyl)- and 4-(4-alkoxyphenyl) oxidovinyl ketone salts with cyanoacetamide; the products were converted into 6-(4-alkylphenyl)- and 6-(4-alkoxyphe