107491-95-2Relevant academic research and scientific papers
A mild hydrolysis of esters mediated by lithium salts
Mattsson, Sara,Dahlstr?m, Mikael,Karlsson, Staffan
, p. 2497 - 2499 (2007/10/03)
When treated with amine bases such as triethylamine and various lithium salts in wet solvents, esters are efficiently hydrolyzed to the corresponding acids in good yields. Esters incorporating an α- or β-heteroatom with respect to the ester carbonyl group are hydrolyzed rapidly even at room temperature. To further demonstrate the usefulness of this method, one example is provided where hydrolysis of acetylated camphorsultam is mediated by LiBr.
