1075-59-8Relevant articles and documents
4,6-dimethoxy-1,3,5-triazin-2-yl-d-glycosaminides: Novel substrates for transglycosylation reaction catalyzed by exo-d-glucosaminidase from amycolatopsis orientalis
Tanaka, Tomonari,Wada, Tomonori,Noguchi, Masato,Ishihara, Masaki,Kobayashi, Atsushi,Ohnuma, Takayuki,Fukamizo, Tamo,Brzezinski, Ryszard,Shoda, Shin-Ichiro
, p. 634 - 646 (2012)
A novel sugar adduct, 4,6-dimethoxy-1,3,5-triazin-2-yl-d-glucosaminide (GlcN-DMT), has been prepared by the reaction of d-glucosamine (GlcN) and 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium chloride (DMT-MM). The adduct was recognized by exo-d-glucosaminidase (GlcNase) from Amycolatopsis orientalis and transferred the GlcN moiety, giving rise to the corresponding glucosaminides. This chemo-enzymatic process was successfully applied to d-galactosamine (GalN). GalN-DMT prepared directly from GalN and DMT-MM behaved as an efficient glycosyl donor for transfer of the GalN moiety catalyzed by the same enzyme. The introduction of the 4,6-dimethoxy-1,3,5-triazin-2-yl leaving group to the anomeric center significantly enhanced transglycosylating ability, resulting in the efficient glycosidase-catalyzed synthesis of glycosaminides.
Optimized triazine-mediated amidation for efficient and controlled functionalization of hyaluronic acid
Borke, Tina,Winnik, Fran?oise M.,Tenhu, Heikki,Hietala, Sami
, p. 42 - 50 (2015)
Triazine-based coupling agents have the potential to replace carbodiimides in the functionalization of hyaluronic acid (HA) giving derivatives with high degrees of substitution (DS) under mild conditions with excellent efficiency. Kinetics of the triazine
sym-triazine derivatives. 2. Synthesis, properties, and structure of 2-oxo-1,2-dihydro-sym-triazines
Mikhailichenko,Chesniyuk,Zavodnik,Firgand,Konyushkin,Zaplishny
, p. 292 - 299 (2002)
Previously unreported 2-oxo-1,2-dihydro-sym-triazines have been prepared and their alkylation reactions have been studied. It was found that, independently of the structure and nature of the substituent in positions 4 and 6 of the triazine ring or the str
Nitrogen Kinetic Isotope Effects on the Acylation of Aniline
Kaminski, Z. J.,Paneth, P.,O'Leary, M. H.
, p. 5716 - 5718 (1991)
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Privilege Ynone Synthesis via Palladium-Catalyzed Alkynylation of "Super-Active Esters"
Yu, Bo,Sun, Huaming,Xie, Zunyuan,Zhang, Guofang,Xu, Li-Wen,Zhang, Weiqiang,Gao, Ziwei
supporting information, p. 3298 - 3301 (2015/07/15)
A neat palladium-catalyzed alkynylation reaction was developed with "super-active ester" as the carbonyl electrophile, which provides a clean and efficient synthetic protocol for a broad array of ynone compounds under CO-, Cu-, ligand-, and base-free conditions. The superior activity of triazine ester was rationalized by the strong electron-withdrawing ability and the unique affinity of triazine on palladium. A mechanistic experiment clearly demonstrated that the N-Pd coordination of triazine plays a crucial role for the highly efficient C-O activation. (Chemical Equation presented).