1075184-39-2Relevant academic research and scientific papers
Carbocupration-functionalization of arynes: Rapid access to variably ortho-substituted ((E)-3-phenylprop-1-enyl)silanes
Ganta, Ashok,Snowden, Timothy S.
supporting information; experimental part, p. 5103 - 5106 (2009/05/30)
(Chemical Equation Presented) A consecutive three-component coupling reaction involving a lithium di[3-(prop-1-enyltrimethylsilyl)]cuprate, variably substituted ortho-arynes, and a selection of common electrophiles is described. The method affords readily functionalized homobenzylic vinylsilanes with exceptional E-diastereoselectivity and allows for in situ incorporation of carbon- or heteroatom-based electrophiles into the arene.
