Cas 1075200-48-4,(2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate

1075200-48-4

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Basic information

Product Name: (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate
Synonyms: (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate
CAS NO:1075200-48-4
Molecular Formula:
Molecular Weight: 632.954
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate(CAS DataBase Reference)
NIST Chemistry Reference: (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate(1075200-48-4)
EPA Substance Registry System: (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7-(tert-butyldimethylsilyloxy)-9,13-dihydroxy-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate(1075200-48-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1075200-48-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1075200-48-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,2,0 and 0 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1075200-48:
(9*1)+(8*0)+(7*7)+(6*5)+(5*2)+(4*0)+(3*0)+(2*4)+(1*8)=114
114 % 10 = 4
So 1075200-48-4 is a valid CAS Registry Number.

1075200-48-4Upstream product

1075200-48-4Downstream Products

1075200-57-5 (2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R)-methyl 7,9,13-tris(tert-butyldimethylsilyloxy)-17-(4-methoxybenzyloxy)-6,12,14,16-tetramethylheptadeca-2,4,10-trienoate

1075200-48-4Relevant academic research and scientific papers

Improved synthesis of 6-epi-dictyostatin and antitumor efficacy in mice bearing MDA-MB231 human breast cancer xenografts

Eiseman, Julie L.,Bai, Lihua,Jung, Won-Hyuk,Moura-Letts, Gustavo,Day, Billy W.,Curran, Dennis P.

, p. 6650 - 6653 (2008)

Structure-activity studies centered on the naturally occurring antitumor agent dictyostatin have recently identified several highly active epimers and analogues. From these compounds, 6-epi-dictyostatin was selected for scaleup preparation and evaluation in animals. Here we describe a new total synthesis that produced more than 30 mg of 6-epi-dictyostatin. The compound was found to have potent antitumor activity in SCID mice bearing MDA-MB231 human breast cancer xenografts.

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