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(2Z,4E,6S,7S,9S,10Z,12S,13R,14S,16R,17E,20R,21S,22S,23Z)-methyl 7,9,13-tris(tert-butyldimethylsilyloxy)-21-(4-methoxybenzyloxy)-6,12,14,16,20,22-hexamethyl-19-oxohexacosa-2,4,10,17,23,25-hexaenoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1075200-52-0

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1075200-52-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1075200-52-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,2,0 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1075200-52:
(9*1)+(8*0)+(7*7)+(6*5)+(5*2)+(4*0)+(3*0)+(2*5)+(1*2)=110
110 % 10 = 0
So 1075200-52-0 is a valid CAS Registry Number.

1075200-52-0Relevant academic research and scientific papers

Improved synthesis of 6-epi-dictyostatin and antitumor efficacy in mice bearing MDA-MB231 human breast cancer xenografts

Eiseman, Julie L.,Bai, Lihua,Jung, Won-Hyuk,Moura-Letts, Gustavo,Day, Billy W.,Curran, Dennis P.

supporting information; experimental part, p. 6650 - 6653 (2009/10/23)

Structure-activity studies centered on the naturally occurring antitumor agent dictyostatin have recently identified several highly active epimers and analogues. From these compounds, 6-epi-dictyostatin was selected for scaleup preparation and evaluation in animals. Here we describe a new total synthesis that produced more than 30 mg of 6-epi-dictyostatin. The compound was found to have potent antitumor activity in SCID mice bearing MDA-MB231 human breast cancer xenografts.

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