1075221-97-4Relevant academic research and scientific papers
New iodoreboxetine analogues for SPECT imaging of the noradrenaline transporter
Jobson, Nicola K.,Crawford, Andrew R.,Dewar, Deborah,Pimlott, Sally L.,Sutherland, Andrew
supporting information; experimental part, p. 4940 - 4943 (2009/08/07)
A new route for the stereoselective synthesis of iodinated reboxetine analogues has been developed for the generation of SPECT imaging agents for the noradrenaline transporter (NAT). (2S,3S)- and (2R,3R)-iodoreboxetine were prepared and biological testing against various mono-amine transporters showed these compounds to be potent and selective for NAT.
