1075240-33-3 Usage
Description
C24H29N3O8, also known as N-Methylol Minocycline, is a derivative of Minocycline Hydrochloride (M344800), which is a second-generation tetracycline antibiotic. It possesses potent antibacterial properties and is characterized by its molecular structure containing 24 carbon, 29 hydrogen, 3 nitrogen, and 8 oxygen atoms.
Uses
Used in Pharmaceutical Industry:
C24H29N3O8 is used as an antibacterial agent for the treatment of various bacterial infections. Its application is based on its ability to inhibit bacterial growth by interfering with their protein synthesis, making it a valuable component in the fight against antibiotic-resistant strains.
Used in Research and Development:
In the field of research and development, C24H29N3O8 is utilized for studying the mechanisms of action of tetracycline antibiotics and their potential applications in combating bacterial resistance. This knowledge can lead to the development of new drugs and therapies to address the growing challenge of antibiotic resistance.
Used in Veterinary Medicine:
C24H29N3O8 is also employed in veterinary medicine as an antibacterial agent for treating bacterial infections in animals. Its use helps maintain the health of livestock and pets, ensuring the well-being of both animals and their human caretakers.
Check Digit Verification of cas no
The CAS Registry Mumber 1075240-33-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,5,2,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1075240-33:
(9*1)+(8*0)+(7*7)+(6*5)+(5*2)+(4*4)+(3*0)+(2*3)+(1*3)=123
123 % 10 = 3
So 1075240-33-3 is a valid CAS Registry Number.
1075240-33-3Relevant articles and documents
Synthesis development of an aminomethylcycline antibiotic via an electronically tuned acyliminium Friedel-Crafts reaction
Chung, John Y.L.,Hartner, Frederick W.,Cvetovich, Raymond J.
scheme or table, p. 6095 - 6100 (2009/04/05)
With the goal of improving the synthetic efficiency, the development of a convergent synthesis of a minocycline derivative PTK0796 via an intermolecular acyliminium Friedel-Crafts reaction (Tscherniac-Einhorn reaction) is described. The entire C9 neopentylaminomethyl side chain was installed in one step using an electronically optimized chloromethylacyliminium precursor in 83% yield. Deprotection and re-equilibration to the C4 α-epimer in the presence of CaCl2 and ethanolamine or NaOH afforded the target aminomethylcycline antibiotic. The corresponding crystalline tosylate salt was found to exhibit improved solid state stability.
