107534-13-4Relevant academic research and scientific papers
(η5-C5Me5)2(Me)Ti-OC(Me)=CH2: titanium enolate or titanium alkoxide?
Gibson, Charles P.,Bem, David S.
, p. 23 - 32 (1991)
While proton and carbon NMR spectroscopy suggest that (Cp*)2(Me)Ti-OC(Me)=CH2 (1, Cp* = η5-C5Me5) is a typical O-bound titanium enolate, this material does not exhibit typical enolate reactivity.Specifically, 1 does not react with either methyl iodide or with benzaldehyde.However, some reagents that are typically used in electrophilic attack of metal-alkyl or metal-alkoxide bonds do react with 1.In some cases the electrophile displaces the enolate moiety, while in other cases selectivity for substitution of the titanium-bound methyl group is displayed.Thus the reactivity of 1 is more typical of that expected from a titanium alkoxide or an alkyl titanium rather than a titanium enolate.The possible use of the (Cp*)2(Me)Ti moiety as a protecting group for ketones is discussed.
