1075754-29-8Relevant academic research and scientific papers
Nickel-mediated decarbonylation of simple unstrained ketones through the cleavage of carbon-carbon bonds
Morioka, Toshifumi,Nishizawa, Akihiro,Furukawa, Takayuki,Tobisu, Mamoru,Chatani, Naoto
, p. 1416 - 1419 (2017/02/10)
Despite advances in methods for the decarbonylation of aldehydes, the decarbonylation of ketones has been met with limited success because this process requires the activation of two inert carbon-carbon bonds. All of the decarbonylation reactions of simple unstrained ketones reported to date require the addition of a stoichiometric rhodium complex. We report herein the nickel/N-heterocyclic carbene-mediated decarbonylation of simple diaryl ketones. This reaction shows unique acceleration effects based on the presence of both electron-donating and electron-withdrawing groups.
Mutual activation: Suzuki-Miyaura coupling through direct cleavage of the sp2 C-O bond of naphtholate
Yu, Da-Gang,Shi, Zhang-Jie
supporting information; experimental part, p. 7097 - 7100 (2011/09/30)
Working together: A new approach of mutual activation between naphtholates and aryl boronic acid derivatives by the formation of borates to facilitate the Suzuki-Miyaura coupling through direct cleavage of the sp2 C-O bond by nickel catalysis is described (see scheme; R′: annulated ring system). Various naphtholates and aryl boronic acid derivatives could be directly coupled in good yields. Copyright
Nickel-catalyzed cross-coupling of aryl phosphates with arylboronic acids
Chen, Hu,Huang, Zhongbin,Hu, Xiaoming,Tang, Guo,Xu, Pengxiang,Zhao, Yufen,Cheng, Chien-Hong
experimental part, p. 2338 - 2344 (2011/05/30)
The Suzuki-Miyaura cross-coupling of aryl phosphates using Ni(PCy 3)2Cl2 as an inexpensive, bench-stable catalyst is described. Broad substrate scope and high efficiency are demonstrated by the syntheses of more than 40 biaryls and by constructing complex organic molecules. The poor reactivity of aryl phosphates relative to aryl halides is successfully employed to construct polyarenes by selective cross-coupling using Pd and Ni catalysts.
Biaryl construction via Ni-catalyzed C-O activation of phenolic carboxylates
Guan, Bing-Tao,Wang, Yang,Li, Bi-Jie,Yu, Da-Gang,Shi, Zhang-Jie
supporting information; scheme or table, p. 14468 - 14470 (2009/02/08)
Biaryl scaffolds were constructed via Ni-catalyzed aryl C-O activation by avoiding cleavage of the more reactive acyl C-O bond of aryl carboxylates. Now aryl esters, in general, can be successfully employed in cross-coupling reactions for the first time.
