1075799-80-2

Basic information

• Product Name: 2-(4-fluoro-phenyl)-3-hydroxy-1,3-azaphospholane-3-oxide
• CAS NO: 1075799-80-2
• Molecular Weight: 215.164
• Mol File: 1075799-80-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-fluoro-phenyl)-3-hydroxy-1,3-azaphospholane-3-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluoro-phenyl)-3-hydroxy-1,3-azaphospholane-3-oxide(1075799-80-2)
• EPA Substance Registry System: 2-(4-fluoro-phenyl)-3-hydroxy-1,3-azaphospholane-3-oxide(1075799-80-2)

Safety Data

• Hazardous Substances Data: 1075799-80-2(Hazardous Substances Data)

Upstream product

• 1075799-55-1 2-aminoethyl-H-phosphinic acid hydrochloride 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

Synthesis of P,N-heterocycles from ω-amino-H-phosphinates: Conformationally restricted α-amino acid analogs

(Chemical Equation Presented) P,N-Heterocycles (3-hydroxy-1,3- azaphospholane and 3-hydroxy-1,3-azaphosphorinane-3-oxide) are synthesized in moderate yield from readily available ω-amino-H-phosphinates and aldehydes or ketones via an intramolecular Kabachnik-Fields reaction. The products are conformationally restricted phosphinic analogs of α-amino acids. The multigram-scale syntheses of the H2N(CH2) nPO2H2 phosphinic precursors (n = 1, 2, 3) and some derivatives are also described.