107644-34-8Relevant academic research and scientific papers
Ruthenium-Catalyzed Selective Addition of Carboxylic Acids to Alkynes.A Novel Synthesis of Enol Esters
Mitsudo, Take-aki,Hori, Yoji,Yamakawa, Yasushi,Watanabe, Yoshihisa
, p. 2230 - 2239 (2007/10/02)
Carboxylic acids react with alkynes in the presence of a catalytic amount of bis(ν5-cyclooctadienyl)ruthenium/trialkylphosphine/maleic anhydride in toluene at 60-80 deg.C to give enol esters having a terminal methylene group in good to excellent yields with high regioselectivity.The deuterium distributions in the products of the reaction of acetic acid-d with 1-hexyne and ethyl propargyl carbonate were examined.Kinetic measurments revealed that the rate has first-order dependence on carboxylic acid, alkyne, and the initial concentration of the ruthenium catalyst.
RUTHENIUM COMPLEX CATALYZED SELECTIVE ADDITION OF CARBOXYLIC ACIDS TO ACETYLENES GIVING ENOL ESTERS
Mitsudo, Take-aki,Hori, Yoji,Yamakawa, Yasushi,Watanabe, Yoshihisa
, p. 2125 - 2126 (2007/10/02)
Carboxylic acids react with acetylenes in the presence of a catalytic amount of bis(η5-cyclooctadienyl)ruthenium-PR3-maleic anhydride in toluene to give enol esters in good to excellent yields with high regioselectivity.
