107658-60-6

Basic information

• Product Name: 2-hydroxy-1,2-bis(4-methylphenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one
• CAS NO: 107658-60-6
• Molecular Formula: C₁₉H₁₉N₃O₂
• Molecular Weight: 321.3731
• Mol File: 107658-60-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 566.6°C at 760 mmHg
• Flash Point: 296.5°C
• Density: 1.18g/cm³
• Vapor Pressure: 1.12E-13mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 2-hydroxy-1,2-bis(4-methylphenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-1,2-bis(4-methylphenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one(107658-60-6)
• EPA Substance Registry System: 2-hydroxy-1,2-bis(4-methylphenyl)-3-(1H-1,2,4-triazol-1-yl)propan-1-one(107658-60-6)

Safety Data

• Hazardous Substances Data: 107658-60-6(Hazardous Substances Data)

Usage

Molecular structure

A compound consisting of a 1-prop酮 (1-propanone) group, a 2-hydroxyl group, two 4-methylphenyl groups, and a 3-(1H-1,2,4-triazol-1-yl) group.

Function

Inhibits the production of ergosterol, a crucial component of the fungal cell membrane.

Mechanism of action

Disrupts the integrity and function of the fungal cell membrane by inhibiting ergosterol production.

Common uses

Treats thrush, vaginal yeast infections, and certain types of systemic fungal infections.

Available forms

Oral tablets, oral suspension, and intravenous injection.

Tolerability

Generally well-tolerated with few serious side effects.

Drug interactions

May interact with certain medications, requiring caution during co-administration.

Special patient considerations

Should be used with caution in patients with liver or kidney disease due to potential adverse effects.