107676-62-0Relevant articles and documents
Study of arginine mimetic benzamidine urea derivatives as PAD4 inhibitors
Kurdekar, Vadiraj,Dighe, Satish N.,Jadhav, Hemant R.
, p. 1273 - 1278 (2020/12/04)
Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease, where antibodies are generated against citrullinated proteins. Citrullinated proteins are catalytic products of the Peptidyl Arginine Deiminase 4 (PAD4) enzyme. Since PAD4 acts on peptidyl a
Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking
Eldehna, Wagdy M.,Fares, Mohamed,Ibrahim, Hany S.,Aly, Mohamed H.,Zada, Suher,Ali, Mamdouh M.,Abou-Seri, Sahar M.,Abdel-Aziz, Hatem A.,Abou El Ella, Dalal A.
, p. 89 - 97 (2015/06/22)
In our effort to develop potent and effective agents with anti-proliferative activity towards HepG2 hepatocellular carcinoma cells with potential inhibitory activity against VEGFR-2, a novel series of 1-(4-((2-oxoindolin-3-ylidene)amino)phenyl)-3-arylurea
