107701-96-2Relevant academic research and scientific papers
Microwave-assisted cleavage of epoxides with amines in the presence of the catalytic Zn(OAc)2/1,7-bis(2-benzoic acid)-1,4,7-trioxaheptane (ZnBBATOH)
Eshghi, Hossein,Rahimizadeh, Mohammad,Shoryabi, Abolhassan
, p. 791 - 798 (2005)
We describe a highly regioselective ring opening of epoxides with aromatic amines in the presence of a catalytic amount of Zn(OAc)2 and 1,7-bis(2-benzoic acid)-1,4,7-trioxaheptane under microwave irradiation. The yields of the amino alcohols ar
An efficient protocol for regioselective ring opening of epoxides using sulfated tungstate: Application in synthesis of active pharmaceutical ingredients atenolol, propranolol and ranolazine
Pathare, Sagar P.,Akamanchi, Krishnacharya G.
supporting information, p. 6455 - 6459 (2013/11/19)
Sulfated tungstate was found to be a new and highly efficient catalyst for opening of epoxide rings by amines to give β-amino alcohols with high regioselectivity. Various advantages associated with this novel and environmental friendly protocol include solvent-free conditions, short reaction times, high product yields, simple workup procedure and easy recovery and reusability of the catalyst. This protocol has been applied for the synthesis of active pharmaceutical ingredients atenolol, propranolol and ranolazine.
Thiourea catalyzed aminolysis of epoxides under solvent free conditions. Electronic control of regioselective ring opening
Chimni, Swapandeep Singh,Bala, Neeraj,Dixit, Vaibhav A.,Bharatam, Prasad V.
experimental part, p. 3042 - 3049 (2010/06/14)
A reactant economizing process for the regioselective aminolysis of epoxides using equimolar quantities of reactants catalyzed by the double hydrogen bond donor N,N′-bis[3,5-bis(trifluoromethyl)phenyl]thiourea is reported. Regioselectivity of the reaction
An efficient method for the ring opening of epoxides with aromatic amines by Sb(III) chloride under microwave irradiation
Ghazanfari, Dadkhoda,Hashemi, Mohammed M.,Mottaghi, Mohammad Mehdi,Foroughi, Mohammad Mehdi
experimental part, p. 220 - 221 (2009/08/07)
SbCl3 supported on montmorillonite K-10 is an efficient catalyst for the ring opening of epoxides with aromatic amines under solvent-free conditions and microwave irradiation to give the corresponding b-amino alcohols in high yields with high regioselectivity.
