107735-33-1

Basic information

• Product Name: 2-phenylaminopyridine 1-oxide
• Synonyms: 2-phenylaminopyridine 1-oxide
• CAS NO: 107735-33-1
• Molecular Weight: 186.213
• Mol File: 107735-33-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-phenylaminopyridine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylaminopyridine 1-oxide(107735-33-1)
• EPA Substance Registry System: 2-phenylaminopyridine 1-oxide(107735-33-1)

Safety Data

• Hazardous Substances Data: 107735-33-1(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 591-50-4 iodobenzene 
• 13980-73-9 2-(N-chlorocarbonyl-N-phenyl)aminopyridine 
• 6631-37-4 2-(phenylamino)pyridine 
• 20295-64-1 2-chloropyridine N-oxide hydrochloride 
• 62-53-3 aniline 
• 107735-32-0 2-aminopyridine 

Downstream Products

• 107735-34-2 2-(N-methoxycarbonyl-N-phenyl)aminopyridine 1-oxide 
• 107735-35-3 2-(N-ethoxycarbonyl-N-phenyl)aminopyridine 1-oxide 

Relevant articles and documents

Ligand compound for copper catalyzed aryl halide coupling reaction, catalytic system and coupling reaction

The invention provides a ligand compound capable of being used for copper catalyzed aryl halide coupling reaction, the ligand compound is a three-class compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group, and the invention also provides a catalytic system for the aryl halide coupling reaction. Thecatalytic system comprises a copper catalyst, a compound containing a 2-(substituted or non-substituted) aminopyridine nitrogen-oxygen group adopted as a ligand, alkali and a solvent, and meanwhile, the invention also provides a system for the aryl halide coupling reaction adopting the catalyst system. The compound containing the 2-(substituted or non-substituted) aminopyridine nitrogen oxygen group can be used as the ligand for the copper catalyzed aryl chloride coupling reaction, and the ligand is stable under a strong alkaline condition and can well maintain catalytic activity when being used for the copper-catalyzed aryl chloride coupling reaction. In addition, the copper catalyst adopting the compound as the ligand can particularly effectively promote coupling of copper catalyzed aryl chloride and various nucleophilic reagents which are difficult to generate under conventional conditions, C-N, C-O and C-S bonds are generated, and numerous useful small molecule compounds are synthesized. Therefore, the aryl halide coupling reaction has a very good large-scale application prospect by adopting the copper catalysis system of the ligand.

Evaluation of the Polar-Inductive and Mesomeric Effects exerted on Contiguous Functionalities by N-Oxidopyridinium Groups

The polar-inductive and mesomeric effects (and mixtures thereof) of N-oxipyridinium-2-, -3-, and 4-yl functionalities have been evaluated in terms of the δIB, δR-, and δ-C scales previously defined.Values were generated fr