107750-91-4Relevant academic research and scientific papers
PROTECTION OF IMIDAZOLES AS THEIR β-TRIMETHYLSILYLETHOXYMETHYL (SEM) DERIVATIVES
Lipshutz, Bruce H.,Vaccaro, Wayne,Huff, Bret
, p. 4095 - 4098 (2007/10/02)
Monocyclic 4(5)-substituted imidazoles react with SEM-Cl to afford the corresponding N-SEM derivatives.These aminals readily metalate at C-2 with n-BuLi in THF at -78 deg C and react with various electrophiles.Deprotection may be achieved with either n-Bu
