107757-06-2Relevant articles and documents
ADRENERGIC AMIDINES
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, (2008/06/13)
Disclosed herein are adrenergic compounds represented by the formula STR1 wherein m is 0, 1 or 2; R 1, R 2, R 3 and R. sub.7 are taken from the group consisting of hydrogen, hydroxy, loweralkyl, loweralkoxy, halo, amino, acetamido or NHSO 2 R wherein R is taken from the group consisting of hydrogen or loweralkyl, provided that R 1, R 2, R. sub.3 and R 7 cannot simultaneously be hydrogen or halo, and provided that when one of R 1, R 2, R 3 and R 7 is halo, the others cannot simultaneously be hydrogen and when two of R 1, R 2, R 3 and R 7 are halo, the other two cannot simultaneously be hydrogen and provided that R 1 and R 7 cannot simultaneously be methoxy each when R. sub.2 and R 3 are hydrogen; R. sub.1 and R 2 or R 2 and R 3 or R 3 and R. sub.7 taken together can form a methylenedioxy or ethylenedioxy bridge; or R 1 and R 2 or R 2 and R 3 or R 3 and R. sub.7 taken together with the aromatic ring can form a benzimidazole or indole bridge; and R. sub.4 and R 5 are hydrogen or taken together form a closed ring of the formula STR2 wherein n is 1 or 2, and the combined solid and dashed line represents a single or double bond when n is 1, and R 6 is taken from the group consisting of hydrogen or loweralkyl, and the pharmaceutically acceptable salts thereof.