107769-35-7Relevant academic research and scientific papers
Cyclocondensation Reactions of 3-Amino-2-hydrazino-4(3H)-pyrimidones. Formation of 1,2,4-Triazolopyrimidines and Pyrimidotetrazines
Bitha, Panayota,Hlavka, Joseph J,Lin, Yang-i
, p. 2220 - 2223 (2007/10/02)
3-amino-2hydrazino-4(3H)-pyrimidinones 1, derived from diaminoguanidine and β-keto esters, react readily with ortho esters in hot acetic acid or butanol to give 1,2,4-triazolopyrimidin-7(8H)-ones 2.In acetic acid at room temperature, 1 reacts with ortho esters, dimethylformamide dimethyl acetal, and diethoxymethyl acetate to form 2 and 6H-pyrimidotetrazin-6-ones 3.The latter ring system undergoes a thermal, acid catalyzed, rearrangement to 2.
