107811-54-1

Basic information

• Product Name: 5-(3-aminophenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol
• Synonyms: (+-)-5-(3-Aminophenyl)-8-chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepin-7-ol; 1H-3-Benzazepin-7-ol, 5-(3-aminophenyl)-8-chloro-2,3,4,5-tetrahydro-3-methyl-, (+-)-
• CAS NO: 107811-54-1
• Molecular Formula: C₁₇H₁₉ClN₂O
• Molecular Weight: 302.7986
• Mol File: 107811-54-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 470.3°C at 760 mmHg
• Flash Point: 238.2°C
• Density: 1.251g/cm³
• Vapor Pressure: 1.81E-09mmHg at 25°C
• Refractive Index: 1.636
• CAS DataBase Reference: 5-(3-aminophenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-aminophenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol(107811-54-1)
• EPA Substance Registry System: 5-(3-aminophenyl)-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol(107811-54-1)

Safety Data

• Hazardous Substances Data: 107811-54-1(Hazardous Substances Data)

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 20697-05-6 2-(3-nitrophenyl)oxirane 
• 7569-87-1 3-chloro-4-methoxyphenethylamine 

Relevant articles and documents

Suppression of morphine and cocaine self-administration in rats by a mixed mu antagonist-kappa agonist (N-CBM-TAMO) and a long-acting selective D1 antagonist (AS-300)

N-CBM-TAMO 2 was prepared by the same procedure as used for TAMO 1. It was found to be a short-term kappa agonist and a long-term mu antagonist. The benzazepine 12, (AS-300) was a potent selective D1 antagonist. Both compounds suppressed cocaine and morphine self-administration in rats at doses which did not affect water consumption.