1078151-91-3Relevant academic research and scientific papers
Concise synthesis of dimemorfan (DF) starting from 3-hydroxymorphinan (3-HM)
Kim, Jong Yup,Kim, Hyoung-Chun,Kim, Jeongmin,Lee, Jinhwa
scheme or table, p. 985 - 987 (2009/08/07)
Dimemorfan (DF) has been known to possess neuroprotective properties. While this promising compound deserves further biological evaluation, synthetic methods have not improved since Murakami group unveiled the synthetic efforts in 1972. Herein a succinct synthesis toward DF from commercially available 3-hydroxymorphinan (3-HM) is disclosed. Other morphinan analogs have been effectively prepared by adopting the similar methodology.
