107841-45-2Relevant academic research and scientific papers
REGIOSELECTIVE DEPROTONATION OF 3-METHYL-4,5-DIHYDROISOXAZOLES AND DIASTEREOSELECTIVE REACTION WITH ELECTROPHILES
Annunziata, Rita,Cinquini, Mauro,Cozzi, Franco,Raimondi, Laura
, p. 2129 - 2134 (1986)
Highly regioselective deprotonation of the title compounds is achieved by working with lithium-amide bases of different steric requirement.The effect of a 5-alkoxymethyl group in the Δ2-isoxazoline ring on both the sense and the extent of the stereoselectivity observed in the reaction of C4-anion with electrophiles is discussed.
